I started taking Duloxetine DR (30mg) Yesterday, October 9, 2026.

I’m keeping a note page (paper and pen) of the first two weeks, maybe something good will happen by the end of that time, but may be to soon to tell. Also if something is not good in the that period it will be good to keep comments on it … so I will do that.

I also created a page: Duloxetine DR 30mg on this weblog to track it that way as well.

I’m very concerned about SAD this year. It’s really real for me, and I am not good about that because Migraines and darkens is what I do, so I won’t want too light in my office, it’s mostly dark and I use Night Light on my pc … most of the time. Different levels depend on what I am doing or feeling.

My nighttimes are horrible too, I can’t fall asleep very much, I’m tired, but lay down, and boom. “Hi,” says my brain and on and on and on pictures and talking and planning and a bunch of other junk … So if anything hurts, that will NOT let me sleep, Just one thing hurts and that’s it.

I was getting to sleep ok before using amitriptyline … then on that for a few months I was just so groggy and wanted to sleep at 9:30 give or take all the time. Go to bed and sleep and wake and sleep and wakeup and sleep and wakeup sleep and then wake up around 10am

UGH

So I quit for a week and every day sleeping was harder and harder and my ADHD brain won’t shut up now. I do get some sleep, but it’s a couple of hour after forever to fall asleep, then up, go to the bathroom, check the weather, lay down, forever again. Repeat, repeat, repeat and then I’m up by 5 to 6 am now. Like sleeping is crap and I’d rather be up than laying down. Sounds like how I lived my life until my 40’s.

So yes, before amitriptyline I could go to sleep often, but not every night, it would be horrible if I couldn’t sleep at all.

I was using Gaba with L-Theanine and also 5-HTP … but now on this new medicine I can’t use those.

I have Mag L-Threonate in the evening. That’s it.

So it is difficult and add a migraine in and it’s just so much worse, like yesterday, I was trying to work on it with everything but eletriptan and it just wouldn’t go, so I took one late and eventually it helped but I was tuckered, so was trying to sleep from 8:30pm and it’s tossing and turning and getting comfy, then arm hurts and that’s all I can think of. Then brain makes me look at something else and la la la thinking thinking, and then thinking oh does my head still hurt or not? Then that bridges to my arm and oh man hurts.

Just a miserable existence as myself.

Edit: 10-18-26: I took Benadryl last night, a full pill, and the night before a half-pill. I am feeling so allergic, and my tongue and throat are sore, which is a bad sign for me all my life.

So another day another dollar. More wasted money for meds I can’t take.

With this knowledge I have a hard time thinking of what I’ll do for today’s dose. It’s Sunday, not office hours for doctors. Even so … I don’t want to be told, “just take it for another week and see if it goes away …” kind of BS. I am miserable.




2 responses to “Duloxetine DR 30mg”

  1. Maisy Avatar

    I think my digestion is really off with this medicine so far. Ragingly hungry, eat, feels so full and miserable later. Low level nearly nauseous feeling. Hope it’ll get better after a week on it. We’ll see.

  2. Maisy Avatar

    It comes to this end, after 9 doses I am certain I am allergic to it, my tongue and throat hurt on the right side and even Benadryl can’t touch it.

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